NFL Preseason Week 3: 49ers vs Raiders Predictions, Odds & Best Bets

The 2024 NFL preseason is winding down as September nears. Having said that, there are still three exhibition matchups scheduled for Friday, highlighted by a San Francisco 49ers vs. Las Vegas Raiders showdown at Allegiant Stadium at 10 p.m. ET on the NFL Network.

Even if the stakes are low tonight, NFL preseason games still feature their fair share of betting opportunities. That’s why this article is here to help you get in on the action as we look at the latest 49ers vs. Raiders odds, as well as my pick for this evening’s clash.

NFL Preseason Game Record: 5-3-0

NFL Preseason Best Bet Record: 5-3-0

NFL Preseason Week 3 Betting: Raiders vs 49ers

49ers vs Raiders Preseason Information

• Matchup: San Francisco 49ers (1-1) vs. Las Vegas Raiders (0-2)
• Venue & Location: Allegiant Stadium (Las Vegas, NV)
• Date: Friday, Aug. 23, 2024
• Game Time: 10 p.m. ET
• How to Watch 49ers vs. Raiders: NFL Network, NFL+

SF vs LV Preseason NFL Odds

All NFL preseason odds are courtesy of BetOnline as of Friday, Aug. 23 at 10:32 a.m. ET. Odds from other sportsbooks may also be mentioned in this article.

49ers vs Raiders Spread

• San Francisco 49ers -7 (-120)
• Las Vegas Raiders +7 (+100)

Raiders vs 49ers Over/Under

• Over 32.5 Points (-110)
• Under 32.5 Points (-110)

49ers vs Raiders Moneyline

• San Francisco 49ers (-325)
• Las Vegas Raiders (+270)

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How to Bet on 2024 NFL Season

Hungry to pounce on some NFL futures markets? Are you looking to get in on even more 49ers vs. Raiders betting action at one of your favorite NFL betting sites? Betting News has your football needs covered from now through February!

We have many betting resources, ranging from daily NFL odds and betting predictions to expert picks. You can find them below to help you get started:

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49ers vs Raiders NFL Betting Trends

• San Francisco is 7-2 straight up in its last nine games vs. Las Vegas.
• Las Vegas is 5-0 straight up in its last five games played on Friday.
• San Francisco is 6-1 ATS in its last seven road games.
• Las Vegas is 13-5 ATS in its last 18 games played in August.
• The total hit the Under in five of San Francisco’s last seven games played in August.
• The total hit the Over in four of Las Vegas’ last five games vs. the NFC West.

49ers vs Raiders Predictions & NFL Picks Today (8/23)

As the regular season nears, these teams are hoping to end the NFL preseason on a high note. The 49ers are looking for consecutive wins following last week’s 16-10 win over the New Orleans Saints. Jake Moody hit a trio of field goals as San Francisco’s defense limited New Orleans to 271 total yards across 10 drives.

Meanwhile, the Raiders dropped to 0-2 in the preseason with a 27-12 blowout loss to the Dallas Cowboys. Las Vegas simply couldn’t get anything going on offense despite holding the ball for nearly 33 minutes, resulting in the team’s average scoring margin falling to a minus-8.0 this summer.

There’s a good chance that the Raiders’ preseason skid will continue tonight given that head coach Antonio Pierce has confirmed that the starters won’t be playing tonight. Conversely, 49ers HC Kyle Shanahan revealed that while his players won’t play the entire matchup, his first-team players will see some kind of action at Allegiant Stadium, even if it’s only for a handful of drives.

How many touches will 49ers RB Christian McCaffrey see vs. the Raiders tonight? 

And even though the Raiders are the home team, it isn’t like the Sin City crowd’s support matters given last week’s 15-point loss to the Cowboys at Allegiant Stadium. In fact, the Raiders are now 0-3 ATS with a minus-10.3 average scoring margin in their last three preseason outings.

With that in mind, I’m predicting a San Francisco victory tonight. The fact that the 49ers will at least begin the game with their starters gives them a concrete edge, especially with the Raiders mostly deploying second- and third-string players this evening. It might get closer as the game goes on, however, the potential for the 49ers to open the game with a big lead is too likely to ignore.

Additionally, I like the 49ers covering the 1.5-point first-quarter spread as the best bet. Again, boasting the likes of QB Brock Purdy, RB Christian McCaffrey, and WR Deebo Samuel means the 49ers have a tremendous opportunity to get off to a massive lead early on. Unless the Raiders are suddenly the second coming of the 1985 Chicago Bears, I’m confident that the 49ers will be up by at least two points once the second frame begins.