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#11 North Carolina vs #6 Ole Miss: Odds & Best Bets

Written by: Nate Hornung
Last Updated: Fri Mar 21, 2025, 14:27 PM
Read Time: 5 minutes

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North Carolina Tar Heels Odds
Spread
Total
Moneyline
-1.5
-110
155
-110o
-125
Ole Miss Rebels Odds
Spread
Total
Moneyline
+2.0
-110
156
-110u
+110
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See Picks & Statistics For The GameThe North Carolina Tar Heels won their play in game and “proved” they belonged to be in this Round of 64 matchup against the Ole Miss Rebels. After losing to Auburn in the SEC Semifinals, Chris Beard’s squad faces a red hot Carolina Tar Heels team led by a trio of guards and Hubert Davis.
The Tar Heels have lost to Duke twice recently, but they’ve beaten their other 9 opponents as the offense is firing on all cylinders. Can Ole Miss slow them down and win this game? Or will North Carolina prove the doubters wrong and the committee right once again?
#11 North Carolina Tar Heels vs #6 Ole Miss Rebels: Round of 64

North Carolina rides their momentum into the Round of 64
Matchup Information – UNC vs Ole Miss
- Venue & Location: Fiserv Forum (Milwaukee, WI)
- Date: Friday, March 21st, 2025
- Tip Off: 4:05pm Eastern
- Broadcast: TNT
Betting Odds
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Spread
- UNC -2 (-107)
- Ole Miss +2 (-113)
Money Line
- UNC -127
- Ole Miss +107
Total
- Over 155.5 (-108)
- Under 155.5 (-112)
Rebels Face Tar Heels in NCAA Tournament

Sean Pedulla and the Rebels take on the Tar Heels today
While the Rebels are a very good team and matchup well against Carolina, the Tar Heels offense is a different animal. The Rebels defense has had issues slowing down high powered offenses, and the last team I would want to play right now is North Carolina.
All they’ve heard is how they don’t belong, despite winning 9/11 down the stretch. They went out and demolished San Diego State (who also didn’t belong) and now have the chance to really gain some more momentum and ride it into the Round of 32. North Carolina had a short trip from Dayton to Milwaukee, so I don’t expect jet lag or travel to be an issue, and instead I am leaning on them dominating the pace of play and daring the Rebels to keep up with them.
I certainly like the over, and I lean with Carolina, so while I do endorse both, I’ll take a different approach.
#11 North Carolina Tar Heels vs #6 Ole Miss Rebels Best Bets

RJ Davis and North Carolina have a huge chip on their shoulder this tournament
UNC vs Ole Miss Prediction: UNC Wins & Covers, Over 155.5
Best Bets: North Carolina TT Over 78.5 (-120) BetOnline
I hope I’m not kicking myself later for taking the team total instead of the ML, but regardless, I see North Carolina putting the ball in the hoop. They have much more to play for, and the offense is incredibly dangerous right now.
The Tar Heels are already Top 20 in offensive efficiency and Top 50 in eFG%, but they are playing in the Top 10 in both over their last 10 games. They love to run, and the Rebels are Top 100 in pace as well, meaning we should see plenty of possessions. Ole Miss ranks 159th in eFG% Defense this year, but they are bottom 35 in the nation over their last 10 contests. I think we see plenty of back and forth in this game, and right now North Carolina is simply the much hotter team.
Back the Tar Heels to score plenty and secure a 2nd NCAA Tournament win this year.
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Nate has been a recreational sports bettor for about 5 years. In that time, he has grown to love the pursuit of winners and sticking it to The Man. Nate loves data and uses his understanding of numbers to help him be a more profitable sports gambler, however he will be the first to tell you this game is about more than just stats.
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