Red Sox vs Orioles MLB Predictions, Odds & Best Bets (5/27): AL East Showdown at Camden Yards

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Even though it’s Memorial Day in the United States, the MLB still has a full schedule lined up for Monday, May 27. The action begins at 1:05 p.m. ET when the Boston Red Sox (27-26) take on the rival Baltimore Orioles (33-18) at Camden Yards.

To the fallen heroes who made the ultimate sacrifice for our country, thank you. 🇺🇸#MemorialDay pic.twitter.com/fm04ynno0e

— Red Sox (@RedSox) May 27, 2024

The Red Sox managed to salvage their three-game series against the Milwaukee Brewers with Sunday’s 2-1 victory. Meanwhile, the Orioles are coming off four straight victories over the Chicago White Sox after notching a 4-1 win yesterday.

Can Boston open this series with a win? Or will Baltimore figure out a way to maintain its winning ways?

Those questions — and more — will be answered as we dive into today’s Red Sox vs. Orioles predictions, odds, and MLB best bets.

2024 MLB Betting Picks Record: 22-13-0 (62.9%)

Memorial Day: Red Sox vs Orioles MLB Betting Today (5/27)

Red Sox vs Orioles Game Information

• Matchup: Boston Red Sox (27-26, 16-11 Away) vs. Baltimore Orioles (33-18, 17-10 Home)
• Venue & Location: Camden Yards (Baltimore, MD)
• Date: Monday, May 27, 2024
• Game Time: 1:05 p.m. ET
• How to Watch Red Sox vs. Orioles: NESN

Red Sox vs Orioles MLB Probable Pitchers

• Red Sox: Cooper Criswell (8 games/7 starts — 2-1, 2.86 ERA)
• Orioles: Cole Irvin (9 games/7 starts— 4-2, 3.15 ERA)

Orioles vs Red Sox MLB Odds & Spread

Orioles vs. Red Sox MLB odds are courtesy of BetOnline as of Monday, May 27 at 9:44 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.

Red Sox vs Orioles Run Line

• Boston Red Sox +1.5 (-145)
• Baltimore Orioles -1.5 (+125)

Orioles vs Red Sox Over/Under

• Over 9 Runs (-118)
• Under 9 Runs (-102)

Red Sox vs Orioles Moneyline

• Boston Red Sox (+140)
• Baltimore Orioles (-153)

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Red Sox vs Orioles MLB Betting Trends

• Boston is 6-14 straight up in its last 20 games vs. the AL East.
• Baltimore is 13-6 straight up in its last 19 home games.
• The total hit the Under in 12 of Boston’s last 18 games.
• The total hit the Under in five of Baltimore’s last six games vs. the AL East.
• The total hit the Under in five of the last six Boston-Baltimore matchups at Camden Yards.

Red Sox vs Orioles Predictions & MLB Picks Today (5/27)

Today’s matchup is a close one as both clubs look to get closer to the top of the division. The Orioles enter this afternoon’s showdown just two games back of the New York Yankees for first in the AL East while the Red Sox are nine games away from the top spot.

Having said that, this is the second Red Sox-Orioles series of the 2024 MLB campaign. The rivals clashed for three games at Fenway Park back in April, resulting in a trio of victories for Baltimore as it outscored Boston 23-10 on aggregate while picking up each win by multiple runs.

The one-sided results aren’t anything new as the Orioles are now 9-4 SU in their last 13 games against the Red Sox dating back to the 2023 season. The O’s are also 12-8 SU in the last 20 games between these teams at Camden Yards.

Boston also tends to struggle against the AL East, having lost 14 of its last 20 divisional matchups — including a 4-6 SU record in 2024. On the flip side, Baltimore has won seven of its first nine AL East tilts to begin the year.

The Orioles have fared well against the AL East in 2024. 

The Red Sox have a chance at beating any team as long as Cooper Criswell remains solid on the mound. The 27-year-old righty is off to his best campaign to date, pitching to a 2.86 ERA and 1.125 WHIP through his first eight appearances. He’s also yet to lose on the road as he owns a 1.84 ERA through three away tilts.

Having said that, the Red Sox will have their hands full with Cole Irvin. Not only does the Orioles Hurler own a career-high 3.15 ERA through nine games to begin the 2024 season, but he’s only allowed two runs across 14 2/3 innings in his last three outings at Camden Yards, striking out 11 batters along the way.

The fact that Irvin is a left-handed pitcher could also hurt the Red Sox, who are just 6-9 SU against southpaws this season.

At the end of the day, I’m taking the Orioles to continue their winning streak. Baltimore is playing tremendously and its results at home speak for themselves. The Red Sox haven’t had much luck against lefties or the AL East this season, so look for those trends to continue as the O’s put forth another solid effort.

Plus, with how well both starters have been performing, backing the Under makes a lot of sense — especially when it’s 5-1 in the last six games between these rivals at Camden Yards.

Red Sox vs Orioles MLB Prediction: BAL wins

Best Red Sox vs Orioles Bet: u9 Total Runs (+100)

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Best Red Sox vs Orioles MLB Player Prop (5/27)

When it comes to today’s best Red Sox vs. Orioles player prop, I’m siding with Gunnar Henderson to record over 1.5 total bases (-110).

Henderson has been productive in the last few weeks, racking up 40 total bases in his last 16 games — an average of 2.5 per contest. The 22-year-old infielder has also finished each of his last three home games with the Over on this prop, working out to an average of 5.3 during that stretch.

Having also finished with over 1.5 TBs in the first three games against the Red Sox this season, I’d be shocked if Henderson doesn’t tally at least two total bases this afternoon.

Best Red Sox vs. Orioles MLB Prop Bet: Gunnar Henderson o1.5 Total Bases (-110)

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