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Mets vs Guardians MLB Predictions, Odds & Best Bets (5/21): Will New York Even the Series?
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Written by: Devon Platana
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New York Mets Odds
Spread
Total
Moneyline
0
0
8
-110o
+120
Cleveland Guardians Odds
Spread
Total
Moneyline
0
0
8
-110u
-122
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See Picks & Statistics For The GameToday’s Mets vs. Guardians MLB predictions and best bets are brought to you by BetOnline. BetOnline is a market leader in sports betting, offering various options from MLB odds to the NBA and everything in between.
The New York Mets (21-26) and Cleveland Guardians (31-17) will play the second meeting of their three-game series when they collide for a 6:10 p.m. ET showdown at Progressive Field on Tuesday, May 21.
Can we get a "go Guards" in the group chat?#ForTheLand | #GuardiWWWWins pic.twitter.com/MlOu00GGXY
— Cleveland Guardians (@CleGuardians) May 21, 2024
The Guardians spoiled Francisco Lindor’s homecoming on Monday with a 3-1 victory over the Mets. Left fielder David Fry recorded a two-RBI single early in the game as New York starting pitcher Ben Lively amassed seven strikeouts with one run allowed across 5 2/3 innings for his third win of the season.
Will New York even the series before it’s too late? Or will New York find a way to earn its fifth consecutive victory?
Today’s Mets vs. Guardians showdown features plenty of MLB betting opportunities, so let’s highlight some of them as we look at my prediction and best bets for tonight.
2024 MLB Betting Picks Record: 16-11-0 (59.3%)
Mets vs Guardians MLB Betting Today (5/21)
Mets vs Guardians Game Information
- Matchup: New York Mets (21-26, 11-12 Away) vs. Cleveland Guardians (31-17, 16-6 Home)
- Venue & Location: Progressive Field (Cleveland, OH)
- Date: Tuesday, May 21, 2024
- Game Time: 6:10 p.m. ET
- How to Watch Mets vs. Guardians: SportsNet New York, MLB.TV
Mets vs Guardians MLB Probable Pitchers
- Mets: Adrian Houser (8 games/6 starts — 0-3, 7.44 ERA)
- Guardians: Carlos Carrasco (9 starts— 2-4, 5.16 ERA)
Guardians vs Mets MLB Odds & Spread
Guardians vs. Mets MLB odds are courtesy of BetOnline as of Tuesday, May 21 at 10:05 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.
Mets vs Guardians Run Line
- New York Mets +1.5 (-192)
- Cleveland Guardians -1.5 (+167)
Guardians vs Mets Over/Under
- Over 9 Runs (-116)
- Under 9 Runs (-104)
Mets vs Guardians Moneyline
- New York Mets (+115)
- Cleveland Guardians (-125)
Get 50% up to $1,000 on your MLB predictions today at BetOnline
How to Bet on 2024 MLB Season
Hoping to get in on the 2024 World Series betting action? Want to wager on more than just today’s Mets vs. Guardians tilt? Betting News has your baseball needs covered from March to November.
We have tons of baseball betting resources, ranging from daily MLB odds and betting predictions to expert picks. You can find them below to help you get started:
Mets vs Guardians MLB Betting Trends
- The Mets are 4-10 straight up in their last 14 games vs. the AL Central.
- Cleveland is 5-0 straight up in its last five home games.
- The total hit the Over in six of the Mets’ last seven road games.
- The total hit the Under in four of Cleveland’s last five games.
- The total hit the Over in nine of the last 12 Mets-Guardians matchups at Progressive Field.
Mets vs Guardians Predictions & MLB Picks Today (5/21)
After losing the series-opening contest, the Mets will look to even things up this evening. The 2024 season hasn’t gone all that well for Carlos Mendoza’s club and things have only gotten worse as yesterday’s loss marked New York’s eighth defeat in the last 11 games.
Adding insult to injury is the fact that the Mets are also 5-10 SU in their last 15 road matchups.
The same can’t be said for the Guardians, who are heading in the opposite direction. Cleveland has been on fire, winning four straight outings ahead of tonight’s tilt while outscoring those opponents 22-9 on aggregate with all but one win coming by multiple runs.
Furthermore, the Guardians are on a five-game winning streak at Progressive Field, beating those opponents by an average of 2.8 runs per game.
The Guardians have been racking up wins left and right at Progressive Field lately.
Interestingly enough, yesterday’s victory ended a seven-game losing streak for the Guardians against the Mets. Nevertheless, New York is 4-3 SU in the last seven instances where it was the home club when facing New York.
If the Guardians want to keep their winning streak going, they must defeat Mets SP Adrian Houser. On one hand, the 31-year-old veteran has been putrid as a starter this season, going 0-3 with an 8.16 ERA in six starts. On the other hand, Houser has pitched well since being moved to the bullpen, allowing three runs on four hits with a strikeout across a quarter of innings.
Meanwhile, Cleveland wouldn’t mind if Carlos Carrasco turned back the clock. The Venezuelan righty has played to a 2-4 record with a 5.16 ERA in nine starts, however, he’s allowed exactly one run in two of his three appearances at Progressive Field thus far.
The Guardians need Carlos Carrasco to keep up his stellar home play if they’re going to beat the Mets again today.
After yesterday’s strong effort, let’s back the Guardians to win again today. The Mets have struggled to produce results on the road and their chances of winning tend to drop whenever Houser takes the mound. If Cleveland can get another early lead, I see the home crowd leaving Progressive Field with smiles.
I’m also backing the Guardians on the moneyline. Not only because they’re the better team, but because the Mets are only 17-19 SU against righties this season, whereas the Guardians are 24-15 in that regard. Considering how New York owns the second-worst winning percentage in inter-league games this season (30.0%), backing Cleveland has never made more sense.
Mets vs Guardians MLB Prediction: CLE wins
Best Mets vs Guardians Bet: CLE ML (-125)
Get 50% up to $1,000 on your Mets vs. Guardians MLB predictions today at BetOnline
Best Mets vs Guardians MLB Player Prop (5/21)
Although I have my eye on a few Mets vs. Guardians props, I’m going to go with Pete Alonso to record over 1.5 total bases (+112) today.
Even if I’m taking the Guardians to win, I can’t ignore the Mets slugger’s hot streak. Alonso is slashing .314/.352/.549 across 54 plate appearances in his last 12 games, racking up 16 hits, six doubles, and two home runs along the way. Oh yeah, I forgot to mention that he finished with the Over on this prop nine times during that stretch — a 75.0% success rate.
With the Over being 6-1 in his last seven road games, I’m feeling good about Alonso exceeding expectations again.
Best Mets vs. Guardians MLB Prop Bet: Pete Alonso o1.5 Total Bases (+112)
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Devon is a Master of Journalism graduate who joined the sports betting world in 2020. His favorite leagues to cover are the NHL, NBA and NFL, and has a soft spot for fantasy football specifically. Outside of sports, he enjoys the finer things in life like pasta, live music and getting even more tattoos.
This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Betting News makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.
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