Guardians vs Red Sox MLB Predictions, Odds & Best Bets (4/15): Monday Morning Mayhem

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Monday, April 15's MLB schedule features the Cleveland Guardians (10-5) and Boston Red Sox (9-7) beginning a four-game series at Fenway Park. The first pitch will be thrown unusually early at 11:10 a.m. ET, but that's because it's both One Boston Day and Jackie Robinson Day.

See everyone bright & early tomorrow.

🔗 https://t.co/aB3QKzTdXh pic.twitter.com/BeSIJxJsqu

— Red Sox (@RedSox) April 14, 2024

The Red Sox are on the hunt for their third win in a row after defeating the Los Angeles Angels 5-4 on Sunday. Meanwhile, the Guardians are coming off an 8-7 victory over the New York Yankees that saw them tally three runs in the 10th inning to seal the deal.

So, which side has the better chance of continuing its momentum this morning? And where do the best betting opportunities lie?

Let's discuss both of those questions as we dive into my Guardians vs. Red Sox MLB predictions and picks today.

2024 MLB Betting Picks Record: 9-5-0

Guardians vs Red Sox MLB Betting Today (4/15)

Guardians vs Red Sox Game Information

• Matchup: Cleveland Guardians (10-5, 7-2 Away) vs. Boston Red Sox (9-7, 2-4 Home)
• Venue & Location: Fenway Park (Boston, MA)
• Date: Monday, April 15, 2024
• Game Time: 11:10 a.m. ET
• How to Watch Guardians vs. Red Sox: MLB Network, NESN, Bally Sports Great Lakes

Guardians vs Red Sox MLB Probable Pitchers

• Guardians: Xzavion Curry (0 starts — 0-0, 0.00 ERA)
• Red Sox: Kutter Crawford (3 starts— 0-0, 0.57 ERA)

Red Sox vs Guardians MLB Odds & Spread

Red Sox vs. Guardians MLB odds are courtesy of BetOnline as of Monday, April 15 at 8:45 a.m. ET. Odds from other top online sportsbooks may also be mentioned in this article.

Guardians vs Red Sox Run Line

• Cleveland Guardians +1.5 (-170)
• Boston Red Sox -1.5 (+150)

Red Sox vs Guardians Over/Under

• Over 9 Runs (-119)
• Under 9 Runs (-101)

Guardians vs Red Sox Moneyline

• Cleveland Guardians (+118)
• Boston Red Sox (-128)

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Guardians vs Red Sox MLB Betting Trends

• Cleveland is 7-13 straight up in its last 20 games vs. Boston.
• Boston is 7-2 in its last nine games as the favorite.
• The total hit the Over in four of Cleveland's last five games.
• The total hit the Over in four of Boston's last five games played on Monday.

Guardians vs Red Sox Prediction & MLB Picks Today (4/15):

All eyes will be on the Red Sox to see if they can continue finding home success. Before picking up back-to-back home victories against the Angels, the Red Sox had opened up the 2024 campaign with four consecutive losses at Fenway Park.

Having said that, Alex Cora's club is now 84-84 SU at home dating back to the start of the 2022 MLB season. It's never a good thing when a team's ballpark becomes a neutral playing field.

Meanwhile, the Guardians haven't had any issues playing away from home, boasting a 7-2 SU road record ahead of today's festivities. A consistent offense has been the key behind that away success as Cleveland averages the sixth-most runs, seventh-most hits, fifth-best batting average, and sixth-fewest strikeouts on the road this year.

Additionally, the Guardians are on a four-game winning streak on the road, having outscored those opponents 20-5 on aggregate.

The Guardians have been one of the best teams on the road to begin the 2024 season. 

The 2023 series between these American League teams was even as Cleveland and Boston split the six games. Having said that, it's been the Red Sox who are now 13-7 SU across their last 20 matchups against the Guardians, which includes winning the two most recent clashes at Fenway Park.

The Red Sox also have the benefit of being 7-2 SU in their nine previous outings as the favorite, however, the Guardians are a perfect 4-0 SU as road underdogs in 2024.

If Cleveland wants to continue that trend, Xzavion Curry must pitch well in his season debut. The former 2019 seventh-rounder began the year with Triple-A Columbus, pitching to a 1.29 ERA with eight strikeouts in seven innings across a pair of starts.

Meanwhile, the Red Sox hope that Kutter Crawford maintains his impressive start. The 28-year-old veteran has been one of Boston's best hurlers thus far, recording a 0.57 ERA while averaging 10.3 strikeouts per nine innings in his first three starts of the year. Is it sustainable? Only time will tell.

Kutter Crawford, Dirty 83mph Splitter. ✌️ pic.twitter.com/b4UDjTm4Ui

— Rob Friedman (@PitchingNinja) April 10, 2024

As solid as the Guardians have been, I'm going with the Red Sox on Monday morning. With it being One Boston Day, the Red Sox will be motivated more than ever to send their crowd home happy. It's also difficult to trust Curry when we haven't seen him pitch at the MLB level this season.

With that in mind, let's take the Red Sox on the moneyline, too. Again, Boston is 7-2 SU in its last nine games as the favorite and has gotten the better of Cleveland over the last few years. As long as Crawford remains steady on the mound, the Red Sox are on the pathway to victory.

Guardians vs Red Sox MLB Prediction: BOS wins

Best Guardians vs Red Sox Bet: BOS ML (-128)

Get 50% up to $1,000 on your Guardians vs. Red Sox MLB predictions today at BetOnline

Best Guardians vs Red Sox MLB Player Prop (4/15)

Guardians vs. Red Sox prop bets are currently unavailable on BetOnline. That's why we're going to Bovada to back Tyler O'Neil to finish with over 1.5 total bases (-145).

O'Neil has been nothing short of superb since joining the Red Sox over the offseason. The Canadian outfielder has excelled at racking up bases, averaging 2.5 TBs per game, which has a lot to do with his MLB-leading seven home runs. Even though he's "only" finished with the Over six times through 14 games, he's coming off a 5-TB performance on Sunday.

With 10 TBs in his last four games against the Guardians, I'm confident in O'Neil's ability to come through on this prop.

Guardians vs Red Sox MLB Prop Bet: Tyler O'Neil o1.5 Total Bases (-145)

Get 50% up to $750 on your Guardians vs. Red Sox MLB picks today at Bovada

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